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Should it be considered a biomarker of healthy aging?


  • Sandro Freitas Faculdade de Motricidade Humana, Universidade de Lisboa
  • Carlos Cruz-Montecinos Department of Physical Therapy, Faculty of Medicine, University of Chile, Santiago, Chile
  • Sébastien Ratel AME2P, EA 3533, Clermont-Auvergne University, Clermont-Ferrand, France
  • Ronei S. Pinto School of Physical Education, Physiotherapy and Dance, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil



dynapenia, health, sedentarism, sarcopenia, neuromuscular function, quality of life


To identify biomarkers that precede the human function decline and independence during lifespan, two important concepts have been introduced in the last decades: sarcopenia and dynapenia. While the former is originally focused on skeletal muscle loss, the latter is on maximal strength loss. Although the dynapenia concept foresees the inclusion of skeletal muscle power, in practical terms, this has not been specifically addressed. For instance, only 2 out of 220 studies published between 2008 and 2023 have directly measured muscle power to classify individuals with dynapenia. As previous studies have shown a greater relevance of skeletal muscle power in healthy aging, we hereby propose the introduction of the term named “powerpenia” to specifically reflect the loss of skeletal muscle power along lifespan. Together with sarcopenia and dynapenia, we contend that powerpenia should be considered a biomarker of healthy aging.


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